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      HomeProduct ApplicationAn Overview of Markers for Neuronal Cells

      An Overview of Markers for Neuronal Cells

      Research on neural cells helps unveil brain mechanisms, underpinning the diagnosis, treatment, and drug development for neurological disorders. This propels advances in neuroscience and related fields.Neural cells are mainly grouped into two key categories:neurons and neuroglial cells.

       

      Neurons: The most basic structural and functional units of the nervous system, neurons are electrically excitable cells in the central (CNS) and peripheral (PNS) nervous systems. They transmit and receive electrical impulses and neurochemical signals to process information. Common markers include:

       

      Schematic diagram of a neuron

       

      NeuN: A neuronal nuclear protein (also called Fox-3 or RBFOX3) expressed only in post-mitotic neurons, primarily used to label neuronal nuclei.

       

      Mouse brain tissue (WB)  Rat brain tissue (IHC) Mouse cerebral cortex (IHC)

       

      β3-tubulin (TUBB3): A commonly used intracellular protein marker specific to neurons in research.

      MAP2: Microtubule-associated protein 2, mainly found in the cell body and dendrites of neurons.

      Neurofilament: Includes 160kDa neurofilament medium subunit, 200kDa neurofilament heavy subunit, etc.

      Synaptophysin: A marker of synaptic vesicles.

       

      Catalog No.

      Product Name

      Application

      Reactivity

      abs110388

      Rabbit anti-TUBB3 Polyclonal Antibody(N-term)

      WB/IHC-P/FCM

      Human, Mouse

      abs158364

      Mouse anti-MAP2 Monoclonal Antibody(3B5)

      IHC/ IF

      Human, Mouse, Rat

       

      Neuroglial cells: These cells, the other major type in neural tissue besides neurons, are widely distributed in the central and peripheral nervous systems. In mammals, the ratio of neuroglial cells to neurons is about 10:1. There are four types of neuroglial cells in the brain and spinal cord, mainly including:

       

      Astrocytes: The most common type of glial cells in the central nervous system.

       

      abs115050  Rabbit anti-GFAP Polyclonal Antibody

      Mouse brain tissue (WB) U-251MG cells (IF) Rat brain (IHC)

       

      Markers include glial fibrillary acidic protein (GFAP), glutamine synthetase, S100β, ALDH1L1, etc.

       

      Catalog No.

      Product Name

      Application

      Reactivity

      abs115050

      Rabbit anti-GFAP Polyclonal Antibody

      WB/IHC-P/IF/ICC

      Human, Mouse, Rat

      abs125057

      Rabbit anti-Glutamine Synthetase Polyclonal Antibody

      WB/IHC-P/IHC-F/IF/ELISA

      Human

      abs125582

      Rabbit anti-ALDH1L1 Monoclonal Antibody

      WB/IHC-P/IHC-F/IF/ELISA

      Mouse, Rat

       

      Oligodendrocytes: These are special types of glial cells mainly responsible for forming myelin sheaths.

       

      abs159592  Rabbit anti-MOG Monoclonal Antibody(4K8)

      Rat brain tissue (WB) SHSY5Y(IF)

       

      Markers include myelin oligodendrocyte glycoprotein (MOG), myelin-associated glycoprotein (MAG), myelin basic protein (MBP), Olig2, Olig3, SOX10, etc.

       

      Catalog No.

      Product Name

      Application

      Reactivity

      abs159592

      Rabbit anti-MOG Monoclonal Antibody(4K8)

      WB/IF

      Rat

      abs115687

      Rabbit anti-MBP Polyclonal Antibody

      WB/IHC-F/IF/ELISA

      Human, Mouse, Rat

      abs120823

      Rabbit anti-Olig2 Recombinant Monoclonal Antibody(648-155)

      IF

      Human, Mouse, Rat

       

      Microglia: Derived from the yolk sac, these are the resident macrophages of the central nervous system.

       

      abs173681 Rabbit anti-TMEM119 Recombinant Monoclonal Antibody(S-838-46)

      SH-SY5Y(WB) SH-SY5Y (ICC)  SH-SY5Y(FCM)

       

      Markers include TMEM119, CD11b, CD45, Iba1, CX3CR1, F4/80, CD68, CD40, etc.

       

      Catalog No.

      Product Name

      Application

      Reactivity

      abs133250

      Rabbit anti-CD11b Recombinant Monoclonal Antibody(058-44)

      WB/IP/ IHC-P

      Human

      abs133251

      Rabbit anti-CD45 Recombinant Monoclonal Antibody(R035)

      WB/ IHC-P

      Human

      abs122767

      Rabbit anti-AIF1 Polyclonal Antibody

      WB/IHC-P/IHC-F/FCM/ELISA

      Human, Mouse, Rat, Pig

      abs137239

      Rabbit anti-F4/80 Recombinant Monoclonal Antibody(313-49)

      WB/ IHC-P

      Mouse, Rat

      abs137004

      Rabbit anti-CD68 Recombinant Monoclonal Antibody(R025)

      IHC-P

      Human

       

       

      Absin provides antibodies, proteins, ELISA kits, cell culture, detection kits, and other research reagents. If you have any product needs, please contact us.

      Absin Bioscience Inc.
      Email: worldwide@absin.cn

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      May 27, 2025

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