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An Overview of Markers for Neuronal Cells
Research on neural cells helps unveil brain mechanisms, underpinning the diagnosis, treatment, and drug development for neurological disorders. This propels advances in neuroscience and related fields.Neural cells are mainly grouped into two key categories:neurons and neuroglial cells.
Neurons: The most basic structural and functional units of the nervous system, neurons are electrically excitable cells in the central (CNS) and peripheral (PNS) nervous systems. They transmit and receive electrical impulses and neurochemical signals to process information. Common markers include:
Schematic diagram of a neuron
NeuN: A neuronal nuclear protein (also called Fox-3 or RBFOX3) expressed only in post-mitotic neurons, primarily used to label neuronal nuclei.
Mouse brain tissue (WB) Rat brain tissue (IHC) Mouse cerebral cortex (IHC)
β3-tubulin (TUBB3): A commonly used intracellular protein marker specific to neurons in research.
MAP2: Microtubule-associated protein 2, mainly found in the cell body and dendrites of neurons.
Neurofilament: Includes 160kDa neurofilament medium subunit, 200kDa neurofilament heavy subunit, etc.
Synaptophysin: A marker of synaptic vesicles.
Catalog No. |
Product Name |
Application |
Reactivity |
Rabbit anti-TUBB3 Polyclonal Antibody(N-term) |
WB/IHC-P/FCM |
Human, Mouse |
|
Mouse anti-MAP2 Monoclonal Antibody(3B5) |
IHC/ IF |
Human, Mouse, Rat |
Neuroglial cells: These cells, the other major type in neural tissue besides neurons, are widely distributed in the central and peripheral nervous systems. In mammals, the ratio of neuroglial cells to neurons is about 10:1. There are four types of neuroglial cells in the brain and spinal cord, mainly including:
Astrocytes: The most common type of glial cells in the central nervous system.
abs115050 Rabbit anti-GFAP Polyclonal Antibody
Mouse brain tissue (WB) U-251MG cells (IF) Rat brain (IHC)
Markers include glial fibrillary acidic protein (GFAP), glutamine synthetase, S100β, ALDH1L1, etc.
Catalog No. |
Product Name |
Application |
Reactivity |
Rabbit anti-GFAP Polyclonal Antibody |
WB/IHC-P/IF/ICC |
Human, Mouse, Rat |
|
Rabbit anti-Glutamine Synthetase Polyclonal Antibody |
WB/IHC-P/IHC-F/IF/ELISA |
Human |
|
Rabbit anti-ALDH1L1 Monoclonal Antibody |
WB/IHC-P/IHC-F/IF/ELISA |
Mouse, Rat |
Oligodendrocytes: These are special types of glial cells mainly responsible for forming myelin sheaths.
abs159592 Rabbit anti-MOG Monoclonal Antibody(4K8)
Rat brain tissue (WB) SHSY5Y(IF)
Markers include myelin oligodendrocyte glycoprotein (MOG), myelin-associated glycoprotein (MAG), myelin basic protein (MBP), Olig2, Olig3, SOX10, etc.
Catalog No. |
Product Name |
Application |
Reactivity |
Rabbit anti-MOG Monoclonal Antibody(4K8) |
WB/IF |
Rat |
|
Rabbit anti-MBP Polyclonal Antibody |
WB/IHC-F/IF/ELISA |
Human, Mouse, Rat |
|
Rabbit anti-Olig2 Recombinant Monoclonal Antibody(648-155) |
IF |
Human, Mouse, Rat |
Microglia: Derived from the yolk sac, these are the resident macrophages of the central nervous system.
abs173681 Rabbit anti-TMEM119 Recombinant Monoclonal Antibody(S-838-46)
SH-SY5Y(WB) SH-SY5Y (ICC) SH-SY5Y(FCM)
Markers include TMEM119, CD11b, CD45, Iba1, CX3CR1, F4/80, CD68, CD40, etc.
Catalog No. |
Product Name |
Application |
Reactivity |
Rabbit anti-CD11b Recombinant Monoclonal Antibody(058-44) |
WB/IP/ IHC-P |
Human |
|
Rabbit anti-CD45 Recombinant Monoclonal Antibody(R035) |
WB/ IHC-P |
Human |
|
Rabbit anti-AIF1 Polyclonal Antibody |
WB/IHC-P/IHC-F/FCM/ELISA |
Human, Mouse, Rat, Pig |
|
Rabbit anti-F4/80 Recombinant Monoclonal Antibody(313-49) |
WB/ IHC-P |
Mouse, Rat |
|
Rabbit anti-CD68 Recombinant Monoclonal Antibody(R025) |
IHC-P |
Human |
Absin provides antibodies, proteins, ELISA kits, cell culture, detection kits, and other research reagents. If you have any product needs, please contact us.
Absin Bioscience Inc. |
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May 27, 2025
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