Leveraging Mitochondria-Endoplasmic Reticulum Functional Interplay With an On-Demand Nanoparticle to Boost mtDNA-Based STING Immunotherapy

Han Chen, Haijing Qu, Yuqing Pan, Wei Cheng, Jie Wu, Ning Wang, Jiaqi Shen, Wei Meng, Zejian Wang, Xiangdong Xue

Advanced Materials. 2026 Jul 17 .

Influencing factors：29.1

Amplifying STING activation by biomimetic manganese mRNA nanovaccines for local and systemic cancer immunotherapy

Chunyan He a b , Changzhou Shi a b , Mingxi Fang a b , Pengzhao Chang a b , Pingfu Hou c , Yingying Zhang a b , Jingjing Li

Journal of Controlled Release. 2026 Jul 10 .

Influencing factors：11.5

p38 MAP kinase senses short-chain fatty acids to attenuate Toll-like receptor signaling and intestinal inflammation

Qingang Wu 1,2,3,†, Rongkai Shi 1,2,3,†, Liwei Xiao 1,2,3,†, Xuxiao He 1,2,3,†, Zhuoneng Chen 4,†, Hong Zhao 1,2,3, Junwei Liu 1,2,3, Shudi Luo 1,2,3, Xiaoming Jiang 1,2,3, Dong Guo 1,2,3, Ying Meng 1,2,3, Rongxuan Zhu 1,2,3, Shan Li 1,2,3, Min Li 1,2,3, Guijun Liu 1,2,3, Suyao Li 1,2,3, Qingqing Yang 1,2,3, Zhe Shen 4,*, Zhimin Lu

Sci Adv. 2026 Jul 10 ; 28:-

Influencing factors：13.9

CHAC2-mediated glutathione metabolic reprogramming drives N1 polarization of bone marrow neutrophils and exacerbates inflammatory comorbidities

Yuting Niu 1,#, Yuman Li 1,#, Shiyu Sun 1,#, Chenyu Deng 1,2, Fan He 1, Yiming Chen 1, Tiansong Xu 1,3, Zhewen Hu 1, Gai Yang 1, Leran Li 1, Boon Chin Heng 4, Yan Lv 5,✉, Ying Huang 1,✉, Xuliang Deng

Int J Oral Sci. 2026 Jul 9 .

Influencing factors：17.6

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

Ning Wang 1,2, Ruiqi Sun 1,2, Yang Fu 1,2, Zhonghan Wu 3, Xinyu Tong 1,2, Hong Tang 1,2, Wentao Zhao 1,2, Zhi Liang 1,2, Jintao Zheng 1,2, Yanan Guan 1,2, Ke Zhou 3, Penghong Song 1,2, Shusen Zheng 1,2,✉, Hangxiang Wang 1,2,✉, Haiyang Xie

Adv Sci (Weinh). 2026 Jul 7 .

Influencing factors：14.1

Targeting adenosine 2A receptor signaling suppresses vascular calcification by restraining smooth muscle osteogenic differentiation

Yaqi Zhou a,b, Dingwei Zhao b,c, Qian Ma c, Sujin Lee d, Kangsan Roh d, Yongfeng Cai c, Jiean Xu a,e, Qiuhua Yang f, Qingen Da b, Zhiping Liu e, Kunfu Ouyang b, Eric JBelin de Chantemele e, Mei Hong b, Clint L Miller g,h, Rajeev Malhotra d, Chunxiang Zhang i,*, Suowen Xu j,k,l,*, Yuqing Huo

Pharmacol Res. 2026 Jul 4 .

Influencing factors：12.2