Amplifying STING activation by biomimetic manganese mRNA nanovaccines for local and systemic cancer immunotherapy

Chunyan He a b , Changzhou Shi a b , Mingxi Fang a b , Pengzhao Chang a b , Pingfu Hou c , Yingying Zhang a b , Jingjing Li

Journal of Controlled Release. 2026 Jul 10 .

Influencing factors：11.5

Overexpression of HIF-1α via small activating RNA enhances CAR-T cell function in hypoxic microenvironments

Na Huang a b c , Qi Chen a b c , Xiqian Zhang a b c , Muhammad Asad Farooq b c , Wanjun He b c , Kai Cui b c , Songshan Zhu b c , Iqra Ajmal b c , Dan Jiang b c , Guangxian Xu

Pharmacological Research. 2026 Jul 1 .

Influencing factors：10.5

An injectable, dual-crosslinked polypeptide hydrogel encapsulating resiquimod-loaded nanoparticles as a long-lasting immunoprotective tumor vaccine

Jiaxuan Yang a b , Yijun Wu a b , Yunan Yuan a b , Fujiang Li a b , Ruonan Huang a b , Qian Cheng a b , Yan Rong a , Xuesi Chen a b , Chaoliang He

Journal of Controlled Release. 2026 Jun 10 .

Influencing factors：11.5

Myeloid Mas drives pyruvate kinase M2-mediated Spi1 lactylation to fuel inflammatory senescence in MASLD

Luying Zhao 1,#, Shujing Xu 1,#, Shikai Qiao 1,#, Zhe Wang 1,#, Shenglan Wang 1,#, Chun Liu 1, Shuo Zhang 1, Peng Wang 2, Xianghua Sun 3, Shanshan Li 4, Li Chen 1, Xiaokun Zhang 1, Chengxi Hu 5, Yongping Zhou 5, Lu Xia 1,✉, Changqing Yang 1,✉, Jing Li

Signal Transduct Target Ther. 2026 May 19 .

Influencing factors：52.7

Antigen spreading mediates heterogeneous solid tumor eradication by DNA demethylating agent-programmed CAR T cells

Yelei Guo 1,†, Chuan Tong 1,†, Jianshu Wei 2,†, Zhiqiang Wu 1, Yuting Lu 1, Fuxin Han 1, Yipeng Zhang 1, Chunmeng Wang 1, Jinhong Shi 1, Fengxia Shi 1, Yao Wang 1,*, Weidong Han

Sci Adv. 2026 May 8 .

Influencing factors：12.5

The m6A reader IGF2BP2 promotes hepatocellular carcinoma progression via enhancing RELB stability

Hehua Ma 1, Yuxin Hong 2, Zhi Xu 1, Zuyi Weng 1, Yuanxun Yang 1, Wei Song 1,2,✉, Juan Li

Mol Biomed. 2026 May 7 .

Influencing factors：10.1