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GSDME mediated pyroptosis drives CCL5 secretion and dictates proteasome inhibitor efficacy in solid tumors
Dongyang Tang, Josh Haipeng Lei, Shiqi Lin, Jingbo Zhou, Xiaoran Wu, Yunfeng Qiao, Heng Sun, Qianqian Chen, Fuqiang Xing, Xiaojin Wang, Xiaoling Xu, Chu-Xia Deng
2026 Aug 14 ; Pharmacological Research:-
Influencing factors：12.2
Proteogenomic characterization of pulmonary large-cell neuroendocrine carcinoma identifies molecular features and therapeutic strategy
Lele Zhang 1,2,†, Liangdong Sun 1,†, Shengnan Duan 3,†, Yilv Yan 1,†, Jinyi Song 3,†, Linghui Xia 3,†, Huansha Yu 4,†, Jijun Sun 1,†, Junjie Hu 1, Di Wang 5, Lu Han 1,2, Jue Wang 1, Yan Chen 1, Hu Zhou 6,*, Chen Wang 3,*, Haiyang Hu 2,*, Ming Ding 3,*, Peng Zhang
Sci Adv. 2026 Aug 12 ; 33:-
Influencing factors：13.9
Mito-TEMPO improves survival rates in npc1-knockout zebrafish by reducing oxidative stress and enhancing mitophagy via Sod2
Wenhao Zhao 1,2, Xudong Hu 1,3, Ruyi Wang 1,2, Han Zhang 1,2, Man Zhou 1,2, Hong Cao
Sci Adv. 2026 Aug 12 ; 33:-
Influencing factors：13.9
EP300-Mediated MTF1-K218 Lactylation Buffers AR-Driven Copper Overload to Suppress Cuproptosis in Castration-Resistant Prostate Cancer
Kai Li 1, Yong Wei 1, Yongshan Li 1, Yuxiang Dong 1, Jiancheng Lv 2, Mingzhi Yuan 3,4,5, Ao Shen 4,5, Fuyang Liu 1, Yetao Zhang 1, Youjian Li 1, Ruixi Yu 6, Yang Liu 7, Tong Zhao 1, Jun Wang 1, Kai Zhou 8, Zongyao Fan 1, Manning Wang 4,5, Jun Xu 3, Mulong Du 1,9,✉, Min Gu 1,✉, Bing Yao 10,11,✉, Qingyi Zhu
Adv Sci (Weinh). 2026 Aug 11 .
Influencing factors：14.1
GM-CSF Promotes Neutrophil PD-L1 Expression Through the VEGFR-2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma
Fangxing Zhu 1,2,3,4,5, Yuanhe You 2,3,4,5, Yiyi Zhang 3,4,5,6, Yibin Dai 1, Xinyu Zhou 2,3,4,5, Yong Fu 7, Xi Lu 3,4,5,8, Yingying Huang 1, Zhihang Zhou 1, Ronghui Xia 3,4,5,6, Wutong Ju 2,3,4,5, Zhaoqi Yuan 9,✉, Laiping Zhong 1,✉, Tongchao Zhao
Adv Sci (Weinh). 2026 Aug 6 .
Influencing factors：14.1
Novel mitophagy activator TJ0113 restricts cytosolic mtDNA to suppress ZBP1-driven inflammation in acute lung injury
Xiaohan Chen a,1, Shunpeng Xing b,1, Xufeng Cen c,1, Jikai Shen c,d,e,1, Jiwei Zhu a, Xu Lin a, Le Xu c, Fengqi Wang c, Yanan Tian c, Xuan Lai c, Yuejia Luo c, Hongguang Xia c,d,e,⁎, Jian Hu a,⁎⁎, Luming Wang
Redox Biol. 2026 Aug 6 .
Influencing factors：16.2