Amplifying STING activation by biomimetic manganese mRNA nanovaccines for local and systemic cancer immunotherapy

Chunyan He a b , Changzhou Shi a b , Mingxi Fang a b , Pengzhao Chang a b , Pingfu Hou c , Yingying Zhang a b , Jingjing Li

Journal of Controlled Release. 2026 Jul 10 .

Influencing factors：11.5

Overexpression of HIF-1α via small activating RNA enhances CAR-T cell function in hypoxic microenvironments

Na Huang a b c , Qi Chen a b c , Xiqian Zhang a b c , Muhammad Asad Farooq b c , Wanjun He b c , Kai Cui b c , Songshan Zhu b c , Iqra Ajmal b c , Dan Jiang b c , Guangxian Xu

Pharmacological Research. 2026 Jul 1 .

Influencing factors：10.5

CD28-Targeted Enzyme-Responsive Conformation-Switching Peptide Self-Assembly for Selective T-Cell Acute Lymphoblastic Leukemia (T-ALL) Therapy

Jun Li, Ziyu Jia, Dekun Li, Zhi-Wen Hu, Yinghao Ding, Shengyi Zhang, Shengkun Tuo, Zhimou Yang, Huisheng Fu, Ling Wang, Man-Di Wang

Advanced Science. 2026 Jun 18 .

Influencing factors：14.1

Tumor-microenvironment-modulating microspheres to augment tumor-infiltrating lymphocyte therapy against solid tumors

Mingkang Li1,2 ∙ Shen Yan1 ∙ Xiaoying Yan2 ∙ Ziwei Nie1 ∙ Haihan Wang2 ∙ Qiaofeng Li2 ∙ Haoqi Liu3 ∙ Wenzhuo Yu2 ∙ Shuai Zhang2 ∙ Yanbin Liu2 ∙ Hong Chen1 Send email to chenh@suda.edu.cn ∙ Winston Duo Wu1 Send email to duo.wu@suda.edu.cn ∙ Yu Chao2 Send email to ychao@suda.edu.cn ∙ Zhuang Liu

Cell Reports Medicine. 2026 Jun 16 .

Influencing factors：14

Multi-omics reveals microbiota, metabolite, and immunological heterogeneity of age-related endotypes in type 1 diabetes

Lanxin Pan 1,#, Huiling Tan 1,#, Tong Yue 1,✉,#, Yu Ding 1, Zhaohe Gu 1, Xulin Wang 1, Jing Wang 1, Tian Wei 1, Xiaoya Zhang 1, Yu Shi, Shiru Chang 1, Chuang Guo 2, Xueying Zheng 1,✉, Jianping Weng

Signal Transduct Target Ther. 2026 Jun 15 .

Influencing factors：52.7

TELO2-interacting protein 1 (TTI1), a novel Wnt/β-catenin target gene, decreases chemo-sensitivity in colorectal cancer by modulating DNA damage responses

Yuqiao Chen 1,2,#, Zheng Chen 1,3,#, Ya Wang 1,4, Yuanbing Yao 1, Youyu Zhang 2, Wentao Huang 2, Kun Song 5, Fengbo Tan 5, Fei Long 6, Changwei Lin 6, Qian Zhang 7, Wei Zhu 8, Wei Zhuang 2, Jianhua Zhou 8, Heli Liu 5, Shuai Xiao 4, Kai Fu

Mol Biomed. 2026 Jun 12 .

Influencing factors：10.1