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      HomeProduct ApplicationA Comprehensive Overview of Neuronal Cell Markers

      A Comprehensive Overview of Neuronal Cell Markers

      The study of nerve cells helps to reveal the working mechanisms of the brain, provides a theoretical basis for the diagnosis, treatment, and drug development of nervous system diseases, and promotes the development of neuroscience and related fields. Nerve cells are mainly divided into two major categories: neurons and glial cells.
      Neurons: These are the most basic structural and functional units of the nervous system. They are the electrically excitable cells in the central nervous system (CNS) and the peripheral nervous system (PNS), capable of transmitting and receiving electrical impulses and neurochemical signals to process information. Common markers:

       

      Schematic diagram of a neuron

      NeuN:Neuronal nuclear protein, also known as Fox-3 or RBFOX3, is expressed only in post-mitotic neurons and is primarily used for the labeling of neuronal nuclei.

       

      abs172290  Rabbit anti-NeuN Recombinant Monoclonal Antibody(432-1)

      Mouse brain tissue(WB)  Rat brain tissue(IHC) Mouse cerebral cortex(IHC)

      β3-tubulin (TUBB3): This is a commonly used neuronal-specific intracellular protein marker in research.
      MAP2 (Microtubule-Associated Protein 2): It is primarily located in the cell bodies and dendrites of neurons.
      Neurofilaments: These include the 160kDa neurofilament medium chain and the 200kDa neurofilament heavy chain, among others.
      Synaptophysin: This is a marker for synaptic vesicles.

       

      Catalog Number

      Product Name

      Application

      Reactivity

      abs172290

      Rabbit anti-NeuN Recombinant Monoclonal Antibody(432-1)

      WB/IP/IHC/IF/FCM 

      Human, Mouse, Rat

      abs110388

      Rabbit anti-TUBB3 Polyclonal Antibody(N-term)

      WB/IHC-P/FCM

      Human, Mouse

      abs158364

      Mouse anti-MAP2 Monoclonal Antibody(3B5)

      IHC/ IF

      Human, Mouse, Rat

      abs173721

      Rabbit anti-Neurofilament H Recombinant Monoclonal Antibody(S-532-103)

      WB/IHC-P

      Human, Mouse, Rat

       

      Glial cells: These are the other major class of cells in neural tissue, in addition to neurons, and are widely distributed in both the central and peripheral nervous systems. In mammals, the ratio of glial cells to neurons is approximately 10:1. There are four types of glial cells in the brain and spinal cord, mainly including:

      Astrocytes: These are the most common type of glial cells in the central nervous system.

       

      abs115050  Rabbit anti-GFAP Polyclonal Antibody

      Mouse brain tissue(WB) U-251MG Cell(IF)Rat brain(IHC)

       

      Markers: These include Glial Fibrillary Acidic Protein (GFAP), Glutamine Synthetase, S100β, ALDH1L1, and others.

       

      Catalog Number

      Product Name

      Application

      Reactivity

      abs115050

      Rabbit anti-GFAP Polyclonal Antibody

      WB/IHC-P/IF/ICC

      Human, Mouse, Rat

      abs155842

      Mouse anti-S100B Monoclonal Antibody

      WB/IHC-P/IHC-F/ICC/IF/ELISA

      Human, Mouse, Rat

      abs125057

      Rabbit anti-Glutamine Synθse Polyclonal Antibody

      WB/IHC-P/IHC-F/IF/ELISA

      Human

      abs159158

      Rabbit anti-ALDH1L1 Monoclonal Antibody(2E9)

      WB

      Mouse, Rat

      Oligodendrocytes: These are a special type of glial cells that are primarily responsible for the formation of myelin sheaths.

       

      abs159592  Rabbit anti-MOG Monoclonal Antibody(4K8)

      Mouse brain tissue(WB) SHSY5Y(IF)

       

      Markers: These include Myelin Oligodendrocyte Glycoprotein (MOG), Myelin-Associated Glycoprotein (MAG), Myelin Basic Protein (MBP), Olig2, Olig3, SOX10, and others.

       

      Catalog Number

      Product Name

      Application

      Reactivity

      abs159592

      Rabbit anti-MOG Monoclonal Antibody(4K8)

      WB/IF

      Rat

      abs119822

      Rabbit anti-MAG Polyclonal Antibody

      WB/IHC-F/IF/ELISA/FCM

      Human, Mouse, Rat

      abs155504

      Rabbit anti-MBP Polyclonal Antibody

      WB/IHC-F/IF/ELISA

      Human, Mouse, Rat

      abs173531

      Rabbit anti-Olig2 Recombinant Monoclonal Antibody(648-155)

      IF

      Human, Mouse, Rat

      abs104950

      Rabbit anti-OLIG3 Polyclonal Antibody(Center)

      WB

      Human, Mouse

      abs173422

      Rabbit anti-SOX10 Recombinant Monoclonal Antibody(R233)

      WB/ICC/FCM

      Human, Mouse, Rat

       

      Microglia: They originate from the yolk sac and are the resident macrophages of the central nervous system.

       

      abs173681 Rabbit anti-TMEM119 Recombinant Monoclonal Antibody(S-838-46)

      SH-SY5Y(WB) SH-SY5Y (ICC)  SH-SY5Y(FCM)

       

      Markers: These include TMEM119, CD11b, CD45, Iba1, CX3CR1, F4/80, CD68, CD40, and others.

       

      Catalog Number

      Product Name

      Application

      Reactivity

      abs173681

      Rabbit anti-TMEM119 Recombinant Monoclonal Antibody(S-838-46)

      WB/ICC/FCM(Intra)

      Human, Mouse, Rat

      abs133250

      Rabbit anti-CD11b Recombinant Monoclonal Antibody(058-44)

      WB/IP/ IHC-P

      Human

      abs133251

      Rabbit anti-CD45 Recombinant Monoclonal Antibody(R035)

      WB/ IHC-P

      Human

      abs173654

      Rabbit anti-Iba1 Recombinant Monoclonal Antibody(S-484-18)

      WB/ IHC-P

      Human, Mouse, Rat

      abs123697

      Rabbit anti-CX3CR1 Polyclonal Antibody

      WB/IHC-P/IHC-F/FCM/ELISA

      Human, Mouse, Rat

      abs137239

      Rabbit anti-F4/80 Recombinant Monoclonal Antibody(313-49)

      WB/ IHC-P

      Mouse, Rat

      abs137004

      Rabbit anti-CD68 Recombinant Monoclonal Antibody(R025)

      IHC-P

      Human

      abs171669

      Rabbit anti-CD40 Recombinant Monoclonal Antibody(145-45)

      WB/IP/IHC-P/FCM(Extra)

      Human

      Schwann cells: These are the glial cells in the peripheral nervous system that form myelin sheaths.

       

      abs158408 Mouse anti-GAP43 Monoclonal Antibody(10C7)

      Hela, 293T, Mouse Brain, Rat Brain(WB) Rat Brain (IHC)

       

      Markers: These include MPZ, NCAM, GAP43, S100, P75NTR, and others.

       

      Catalog Number

      Product Name

      Application

      Reactivity

      abs146198

      Rabbit anti-MPZ Polyclonal Antibody

      WB

      Human, Mouse, Rat

      abs118208

      Rabbit anti-NCAM1 Polyclonal Antibody

      WB/IP/ IHC-P

      Human, Mouse, Rat

      abs149696

      Mouse anti-GAP43 Monoclonal Antibody

      WB/ IHC

      Human, Mouse, Rat

      abs171609

      Rabbit anti-S100P Recombinant Monoclonal Antibody(070-44)

      IHC

      Human

      abs130295

      Rabbit anti-p75 NGF Receptor Recombinant Monoclonal Antibody(055-42)

      WB/IP/IHC/ICC/FCM(Intra)

      Human, Mouse, Rat

       

      Neural stem cells: These are a population of progenitor cells that exist in the nervous system, with the potential for division and the ability for self-renewal. They can give rise to various types of cells in neural tissue through asymmetric division.

       

      abs131996  Rabbit anti-Vimentin Monoclonal Antibody(029-20)

      SH-SY5Y(FCM)  SH-SY5Y(IF)

       

      Common markers include Nestin, SOX2, CXCR4, Vimentin, and NeuroD1.

       

      Catalog Number

      Product Name

      Application

      Reactivity

      abs137231

      Rabbit anti-Nestin Recombinant Monoclonal Antibody(R112)

      IHC-P/IF/ICC/ FCM(Intra)

      Human

      abs100224

      Mouse anti-SOX2 Monoclonal Antibody(57CT23.3.4)

      WB/IHC/IHC-P/IF FCM

      Human, Mouse

      abs120406

      Rabbit anti-CXCR4 Polyclonal Antibody

      WB/ IHC

      Human, Mouse, Rat

      abs131996

      Rabbit anti-Vimentin Monoclonal Antibody(029-20)

      WB/IHC/ICC

      Human, Mouse

      abs123166

      Rabbit anti-NeuroD1 Polyclonal Antibody

      WB/IHC-P/IHC-F/IF/ICC/ ELISA

      Mouse, Rat

       

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      Absin provides antibodies, proteins, ELISA kits, cell culture, detection kits, and other research reagents. If you have any product needs, please contact us.

      Absin Bioscience Inc.
      Email: worldwide@absin.net

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      June 17, 2025

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