| SKU-Pack Size | Availability | Price | Quantity |
| abs920-2*25ml | In stock | $30.00 | - + |
| abs920-2*50ml | In stock | $60.00 | - + |
| abs920-2*250ml | In stock | $180.00 | - + |
Request bulk quotation| Description | ||
| Description | Western blot substrate luminescence detection reagent can produce chemiluminescence reaction catalyzed by horseradish peroxidase labeled on secondary antibiotic, which can sensitively detect the presence of target protein. ECL substrate chemiluminescence detection kit has been developed based on a new generation of enhanced chemiluminescence substrates, and its composition has been optimized. Low product background, good stability. A chemical reaction catalyzed by horseradish peroxidase (HRP) produces fluorescence, which can be used for X-ray film exposure, direct luminometer detection or fluorescent CCD scanning. | |
| Component | A liquid; B liquid | |
| Protocol | 1. According to the conventional Western blot operation, after secondary antibody incubation, during the last washing, according to the membrane size, 0.5mL solution A and 0.5mL solution B were mixed every 10 cm2 membrane to prepare the luminescence detection working solution. 2. Remove the film with a flat-headed tweezer and gently touch the lower edge of the film with the blotting paper to remove excess liquid from the film. Place the albumen side up on clean cling film (some commercially available cling film may quench the fluorescence when wrapping the imprinted film, so choose high quality cling film). The prepared luminescence detection solution was transferred to the protein membrane with a pipette, which was evenly covered and incubated at room temperature for 2 minutes. 3. Hold the protein membrane with a flat-head tweezers and gently touch the lower edge of the membrane with the blotting paper to remove excess liquid on the membrane. The protein side of the film is up and wrapped in clean plastic wrap. Gently remove the air bubbles and fix them in the X-ray cassette. 4. Place an X-ray film in a dark room on the wrapped film, close the obscura, and expose for 30 seconds to 1 minute. Develop and fix immediately, shortening or extending the exposure time of the next X-ray, depending on its exposure intensity (exposure time can be extended to several hours for weak signals). | |
| Operating Instructions | 1. The head of ECL LIQUID A and LIQUID B must be replaced in the process of absorption. Mutual contamination of liquid A and liquid B will lead to gradual failure of liquid A or liquid B, which will affect the subsequent use effect. 2. After using each solution, please close the bottle cap tightly to prevent failure. In particular, liquid B contains oxidants and is easy to be reduced and invalid. 3. The fluorescence duration of ECL is very long, but the fluorescence becomes stronger within 30 minutes after the initial reaction, and then gradually decreases. Therefore, please pay attention to make full use of this 30 minutes with strong fluorescence for tablet pressing. 4.ECL A liquid and B liquid are harmful to human body, please pay attention to proper protection when operating. For your safety and health, please wear lab coat and disposable gloves. | |
| Overview | ||
| Storage Temp. | Keep at 2-8℃ for 6 months. | |
| Properties | ||
| Synonym | ECL luminescent liquid; ECL luminescence reagent; HRP chemiluminescence substrate | |
| Western blot analysis of Rock-1 expression in Hep G2 (A) and NIH/3T3 (B) whole cell lysates. | ||
| Western blot analysis of NFATc3 isoform expression in Ramos whole cell lysate. | ||
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- Carcinoma-associated fibroblasts derived exosomes modulate breast cancer cell stemness through exonic circHIF1A by miR-580-5p in hypoxic stress
Yanxia Zhan, Junxian Du, Zhihui Min, Li Ma, Wei Zhang, Wei Zhu, Yonglei Liu
Cell Death Discovery. 2021 Jun 12 .
effect： 5.302
- Protective effects of astragaloside IV against hypertension-induced vascular remodeling involves the DNMT1 and TET2 signaling pathway
Qin Yingchun, Xie Yilin, Li Aihua, Zhang Xiaoqin, Yan Zhiqiang
Archives of Biological Sciences. 2021 Jun 08 .
effect： 0.683
- Mesenchymal stem cells ameliorate silica-induced pulmonary fibrosis by inhibition of inflammation and epithelial-mesenchymal transition
Jingjing Wei, Qiuyan Zhao, Guo Yang, Ruoxuan Huang, Chao Li, Yuanmeng Qi, Changfu Hao, Wu Yao
Journal of Cellular and Molecular Medicine. 2021 Jun 02 .
effect： 4.262
- Mesenchymal stem cells ameliorate silica‐induced pulmonary fibrosis by inhibition of inflammation and epithelial‐mesenchymal transition
J Wei, Q Zhao, G Yang, R Huang, C Li
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2021 Jun 02 .
effect： 5.310
- 藏药二十五味鬼臼丸的植物雌激素样作用及其对雌激素受体调控的研究
王琦
青海大学. 2021 Jun 01 .
- 维生素C诱导甲状腺未分化癌8505C细胞铁死亡及重分化的机制研究
王晓雯
江南大学. 2021 Jun 01 .
- Hippo信号通路核心蛋白YAP在小鼠出生后脑发育不同时间点的表达变化
李希凡
桂林医学院. 2021 Jun 01 ; 1
- miRNA-148a-3p通过CANX/MHC-I途径促进结直肠癌免疫逃逸的分子机制研究
郑锦秀
山西医科大学. 2021 May 31 ; 1
- Neonatal Murine Model of Coxsackievirus A2 Infection for the Evaluation of Antiviral Therapeutics and Vaccination
Wangquan Ji, Luwei Qin, Ling Tao, Peiyu Zhu, Ruonan Liang, Guangyuan Zhou, Shuaiyin Chen, Weiguo Zhang, Haiyan Yang, Guangcai Duan, Yuefei Jin
Frontiers in Microbiology. 2021 May 28 .
effect： 4.023
- B7 homolog 6 promotes the progression of cervical cancer
Ruimeng Guo, Guoyan Liu, Changying Li, Xuejing Liu, Yanying Xu, Weina Yang, Fang Wang
Experimental and Therapeutic Medicine. 2021 May 18 .
effect： 1.696
- METTL3-Mediated m6A Methylation Regulates Muscle Stem Cells and Muscle Regeneration by Notch Signaling Pathway
Yu Liang, Hui Han, Qiuchan Xiong, Chunlong Yang, Lu Wang, Jieyi Ma, Shuibin Lin, Yi-Zhou Jiang
Stem Cells International. 2021 May 15 .
effect： 3.676
- 组织因子在胶质瘤中的表达及其与胶质瘤细胞上皮-间质转化的关系
孙莹
吉林大学. 2021 May 01 .
- 球形孢子丝菌黑素对THP-1巨噬细胞自噬的影响及TLRs对其调节作用的研究
关梦琦
吉林大学. 2021 May 01 .
- RNA甲基化m6A修饰在梗阻性肾病肾间质纤维化中的作用及机制研究
李雪艳
中国医科大学. 2021 May 01 ; 2
- circ_0003204 Regulates Cell Growth, Oxidative Stress, and Inflammation in ox-LDL-Induced Vascular Endothelial Cells via Regulating miR-942-5p/HDAC9 Axis
Huan Wan, Ting You, Wei Luo
Frontiers in Cardiovascular Medicine. 2021 Apr 01 .
- Icariin attenuates endothelial-mesenchymal transition via H19/miR-148b-3p/ELF5 in ox-LDL-stimulated HUVECs
Shan Liu, Dong-sheng,Xu, Min Li, Yang Zhang, Qi Li, Teng-teng Li, Li-qun Ren
Molecular Therapy - Nucleic Acids. 2021 Mar 15 .
effect： 8.20
- Pathogenesis Study of Enterovirus 71 Using a Novel Human SCARB2 Knock-In Mouse Model
Yuefei Jin, Tiantian Sun, Guangyuan Zhou, Dong Li, Shuaiyin Chen, Weiguo Zhang, Xueyuan Li, Rongguang Zhang, Haiyan Yang, Guangcai Duan
mSphere. 2021 Mar 10 ; 2
effect： 4.068
- c-Src facilitates tumorigenesis by phosphorylating and activating G6PD
Huanhuan Ma, Fengqiong Zhang, Lin Zhou, Tingyan Cao, Dachao Sun, Shixiong Wen, Jinpei Zhu, Zhaoqianyu Xiong, Ming-Tong Tsau, Mei-Ling Cheng, Li-Man Hung, Yanming Zhou, Qinxi Li
Oncogene. 2021 Mar 08 .
effect： 9.867
- Apocynin prevents reduced myocardial nerve growth factor, contributing to amelioration of myocardial apoptosis and failure
Xi Jie,Hong Yang,Ke Wang,Zong-Feng Zhu,Jia-Pu Wang,Li-Guo Yang,Zi-Jian Yang,Xiao-Juan Zhang,Ai-Ling Wang,Lu Li,Rui-Fang Chi,Fu-Zhong Qin,Bao Li,Bianai Fan
Clinical and Experimental Pharmacology and Physiology. 2021 Mar 01 .
effect： 2.31
- TUDCA调控内质网自噬在矽尘诱导肺部损伤中的作用机制研究
刘佳丽
中国医科大学. 2021 Mar 01 .
- miR-147a靶向MCM3对脉络膜黑色素瘤细胞增殖、迁移、侵袭影响的机制研究
刘然
中国医科大学. 2021 Mar 01 .
- 基于JAK2信号通路探索芦丁缓解小鼠结肠炎作用及相关机制
刘佳妮
大连医科大学. 2021 Mar 01 .
- Circ_0000527 Promotes Retinoblastoma Progression through Modulating miR-98-5p/XIAP Pathway
Binke Yu, Jifei Zhao, Yongxiao Dong
Current Eye Research. 2021 Feb 25 .
effect： 1.754
- N6-methyladenosine-induced circ1662 promotes metastasis of colorectal cancer by accelerating YAP1 nuclear localization
Chen Chen, Weitang Yuan, Quanbo Zhou, Bo Shao, Yuying Guo, Weiwei Wang, Shuaixi Yang, Yaxin Guo, Luyang Zhao, Qin Dang, Xiuxiu Yang, Guixian Wang, Qiaozhen Kang, Zhenyu Ji, Jinbo Liu, Zhenqiang Sun
Theranostics. 2021 Feb 25 ; 9
effect： 8.150
- Overexpression of heat shock protein 70 inhibits epithelial-mesenchymal transition and cell migration induced by transforming growth factor-β in A549 cells
Fengxian Shi, Mingze Ma, Ruonan Zhai, Yanan Ren, Ke Li, Hang Wang, Chunyan Xu, Xiaowen Huang, Na Wang, Fang Zhou, Wu Yao
Cell Stress and Chaperones. 2021 Feb 17 .
- Caspase 3/GSDME-dependent pyroptosis contributes to chemotherapy drug-induced nephrotoxicity
Xiujin Shen, Haibing Wang, Chunhua Weng, Hong Jiang, Jianghua Chen
Cell Death & Disease. 2021 Feb 15 .
effect： 8.469
- NCR3LG1 (B7-H6) is a potential prognostic factor for bladder cancer patients
Linlin Zhao,Tong Lian,Jianmin Li,Shiyao Wei,Hongjie Li,Changying Li, Haitao Wang
Biomarkers. 2021 Feb 10 .
effect： 2.07
- Endometrial extracellular vesicles of recurrent implantation failure patients inhibit the proliferation, migration, and invasion of HTR8/SVneo cells
Chang Liu, Linshuang Li, Meng Wang, Shike Shui, Haixia Yao, Cong Sui, Hanwang Zhang
Journal of Assisted Reproduction and Genetics. 2021 Feb 01 .
effect： 2.829
- 基于MAPK和AKT介导Nrf2/Keap1/p62信号通路扰动自噬促进海马细胞凋亡的雄黄神经毒性研究
杨钊
中国医科大学. 2021 Feb 01 .
- Systematic profiling of the effective ingredients and mechanism of Scabiosa comosa and S. tschilliensis against hepatic fibrosis combined with network pharmacology
Qianwen Chen, Yuanyuan Wang, Feixiang Ma, Mengdi Han, Zhen Wang, Peifeng Xue , Jingkun Lu
Scientific Reports. 2021 Jan 28 .
effect： 4.379
- Effects of Smad4 on the expression of caspase‑3 and Bcl‑2 in human gingival fibroblasts cultured on 3D PLGA scaffolds induced by compressive force
Shuang Zhao, Lan Nan, Yao Wang, Liying Wei, Shuixue Mo
International Journal of Molecular Medicine. 2021 Jan 19 ; 3
effect： 3.098
- TDO2 Promotes the EMT of Hepatocellular Carcinoma Through Kyn-AhR Pathway
Lei Li, Tao Wang, Shanbao Li, Zhengqian Chen, Junyi Wu, Wanyue Cao, Qi Wo, Xuebin Qin, Junming Xu
Frontiers in Oncology. 2021 Jan 19 .
effect： 4.848
- Altered microRNA Profiles of Extracellular Vesicles Secreted by Endometrial Cells from Women with Recurrent Implantation Failure
Chang Liu, Meng Wang, Hanwang Zhang，Cong Sui
Reproductive Sciences. 2021 Jan 11 .
effect： 3.060
- Yangonin inhibits ethanol-induced hepatocyte senescence via miR-194/FXR axis
Renchao Dong, Xiaohui Wang, Lu Wang, Changyuan Wang, Kai Huang, Ting Fu, Kexin Liu, Jingjing Wu, Huijun Sun, Qiang Meng
European Journal of Pharmacology. 2021 Jan 05 .
effect： 4.12
- Transcriptome analysis reveals a protective role of liver X receptor alpha against silica particle-induced experimental silicosis
Wu Yao, Peiyan Yang, Yuanmeng Qi, Luheng Jin, Ahui Zhao, Mingcui Ding, Di Wang, YiPing Li, Chengfu Hao
Science of The Total Environment. 2020 Dec 10 .
effect： 6.551
- Effects of nicorandil on p120 expression in the spinal cord and dorsal root ganglion of rats with chronic postsurgical pain
Sai‑Sai Huang, Su Cao, Cui E. Lu, Yi‑Bin Qin, Jian‑Ping Yang
Molecular Medicine Reports. 2020 Dec 01 ; 6
effect： 2.1
- 具有缓解抑郁功能的短双歧杆菌CCFM1025的研究
田培郡
江南大学. 2020 Dec 01 ; 4
- Exosomes derived from three-dimensional cultured human umbilical cord mesenchymal stem cells ameliorate pulmonary fibrosis in a mouse silicosis model
Chunjie Xu, Jing Zhao, Qiuyue Li, Lin Hou, Yan Wang, Siling Li, Fuyang Jiang, Zhonghui Zhu, Lin Tian
Stem Cell Research & Therapy. 2020 Nov 25 .
effect： 5.99
- Phosphorylated MAPK14 Promotes the Proliferation and Migration of Bladder Cancer Cells by Maintaining RUNX2 Protein Abundance
Liu J, Yu X, Liu B, Yu H, Li Z
Cancer Management and Research. 2020 Nov 06 .
effect： 2.886
- 激活素A参与缺血性脑损伤小胶质细胞极化表型变化的研究
刘洪雨
吉林大学. 2020 Nov 01 .
- 锌指基因1对脑胶质瘤细胞增殖及凋亡能力的影响
郑励力; 孙青芳
神经损伤与功能重建. 2020 Oct 25 ; 10
- The relationship between gestational diabetes mellitus and interleukin 1beta gene polymorphisms in southwest of China
Ting Liu, MD, PhD, Jia-min Deng, MD, Yan-ling Liu, MD, Li Chang, MD, and Yong-mei Jiang, MD, PhD
Medicine. 2020 Oct 23 ; 43
effect： 1.552
- Aberrant expression of oxytocin receptor in endometrium and decidua in women who experienced recurrent implantation failure
Chang Liu M.D., Yuehan Li M.M, Linshuang Li M.M, Shike Shui M.D., Le Yang M.D., Cong Sui M.D., Hanwang Zhang Ph.
F&S Science. 2020 Oct 13 .
- Changes in miR-222 expression, DNA repair capacity, and MDM2-p53 axis in association with low-dose benzene genotoxicity and hematotoxicity
Tong-shuai Wang, Wei Tian, Yan Fang, Kong-rong Guo, An-qi Li, Yuan Sun, Han-tian Wu, Guo-qiao Zheng, Nan-nan Feng, Cai-hong Xing, William W.Au, Dao-yuan Sun, Zhao-lin Xia
Science of The Total Environment. 2020 Oct 03 .
effect： 6.551
- Selenium mitigates cadmium-induced crosstalk between autophagy and endoplasmic reticulum stress via regulating calcium homeostasis in avian leghorn male hepatoma (LMH) cells
Cong Zhang, Li-Li Wang, Chang-Yu Cao, Nan Li, Milton Talukder, Jin-Long Li
Environmental Pollution. 2020 Oct 01 .
effect： 5.714
- Anti‐adipogenesis and metabolism‐regulating effects of heat‐inactivated Streptococcus thermophilus MN‐ZLW‐002
Xiaohong Kang, Huijing Liang, Yating Luo, Zhouyong Li, Fang He, Xue Han, Lanwei Zhang
LETTERS IN APPLIED MICROBIOLOGY. 2020 Sep 27 .
effect： 2.173
- PRV激活三叉神经节细胞NF-κB信号通路的探究
廖少山
贵州大学. 2020 Sep 01 ; 1
- Berberine Inhibits Cell Proliferation by Interfering with Wild-Type and Mutant P53 in Human Glioma Cells
Liu Z, Chen Y, Gao H, Xu W, Zhang C, Lai J, Liu X, Sun Y, Huang H
OncoTargets and Therapy . 2020 Aug 28 .
effect： 3.337
- Cellular effects of PM2.5 from Suzhou, China: relationship to chemical composition and endotoxin content
Lili Xin, Jianshu Wang, Jiaojiao Sun, Chen Zhang, Xing Tong, Jianmei Wan, Jialiang Feng, Hailin Tian & Zengli Zhang
Environmental Science and Pollution Research. 2020 Aug 18 .
effect： 3.056
- 黄芪提取液对糖尿病溃疡大鼠Wnt/β-Catenin信号通路调控表皮干细胞增殖分化的影响
仇莲胤;阙华发;屈可伸;孙伟;郭树豫
世界科学技术-中医药现代化. 2020 Aug 17 ; 7
- EphB4 signaling maintains the contractile phenotype of adult venous smooth muscle cells
Chenzi Yang, Chang Shu, Lunchang Wang, Xin Li, Hao He, Jiehua Li, Jieting Zhu, Yibo Yang, Alan Dardik
Am J Transl Res. 2020 Aug 15 ; 8
effect： 3.375
- Endometrial extracellular vesicles from women with recurrent implantation failure attenuate the growth and invasion of embryos
Chang Liu M.D., Wen Yao M.M., Junning Yao M.D., Linshuang Li M.M., Le Yang M.D., Hanwang Zhang Ph.D., Cong Sui M.D.
Fertility and Sterility. 2020 Aug 01 ; 2
effect： 6.312
- 基于基因组学探究AKBA对大鼠坐骨神经损伤的修复机制
汪瑶
东北农业大学. 2020 Aug 01 .
- EZH2抑制剂GSK126对肺腺癌细胞增殖和凋亡的影响
张爽爽; 贺武斌; 苏荣健; 杜晓媛
吉林大学学报(医学版). 2020 Jul 28 .
- 二氢丹参酮Ⅰ通过核因子κB信号通路抑制卵巢癌进展的研究
彭翔云; 王鹤; 王岚; 李秋萍
中国医院用药评价与分析. 2020 Jun 30 .
- 猪流行性腹泻病毒诱导Vero细胞凋亡的机制研究
杨琳
浙江理工大学. 2020 Jun 07 .
- Arsenic Induces Dysfunctional Autophagy via Dual Regulation of mTOR Pathway and Beclin1-Vps34/PI3K Complex in MLTC-1 Cells
Chen Liang, Zhiyuan Feng, Ram Kumar Manthari, Chong Wang, Yongli Han, Weixiang Fua, Jundong Wang, Jianhai Zhang
Journal of Hazardous Materials. 2020 Jun 05 .
effect： 7.65
- Amlexanox exerts anti-inflammatory actions by targeting phosphodiesterase 4B in lipopolysaccharide-activated macrophages
Yixin Han, Rui Hou, Xiaoyu Zhang, Haibo Liu, Yuan Gao, Ximeng Li, Ruijuan Qi, Runlan Cai, Yun Qi
BBA-MOL CELL RES. 2020 Jun 03 .
effect： 4.105
- miR-31通过靶向SATB2促进结肠炎的机制
刘凯丽
山西医科大学. 2020 Jun 02 .
- mTORC2/AKT调控CD8+T细胞记忆形成的表观遗传学研究
于忠楠
沈阳工业大学. 2020 Jun 02 ; 1
- ADAR1在系统性红斑狼疮中的表达特征及其与血清IFN-α的关系
狄雪琪
郑州大学. 2020 Jun 01 .
- 应用dsRNA对旋毛虫Kazal型丝氨酸蛋白酶抑制剂基因功能的初步研究
于鹏成
东北农业大学. 2020 Jun 01 .
- 氯胺酮联合DHA对脂多糖引起的大鼠抑郁样行为改善作用及其机制的研究
常岱岳
东北农业大学. 2020 Jun 01 .
- 异牡荆素对SK-Hep-1源性肝癌干样细胞特性和miR-34a-5p表达的影响
许畅
湖南师范大学. 2020 Jun 01 ; 1
- 体外培育牛黄治疗果糖诱导非酒精性脂肪性肝病的作用及其机制研究
贺雯茜
华中科技大学. 2020 Jun 01 ; 2
- miR-155-5p对VPA孤独症小鼠行为的影响及机制研究
陈恬
桂林医学院. 2020 Jun 01 ; 3
- 基于TGF-β1/LIMK1信号通路研究解毒通络方对大鼠心肌纤维化的抑制作用
宋晶
长春中医药大学. 2020 Jun 01 .
- 氯胺酮通过多巴胺第二受体对抑郁样大鼠的调节作用
张鑫彤
东北农业大学. 2020 Jun 01 .
- SS31肽对脓毒症心肌损伤的作用及机制研究
刘月
湖北医药学院. 2020 Jun 01 .
- MiR-103a-3p promotes tumour glycolysis in colorectal cancer via Hippo/YAP1/HIF1A axis
Zhenqiang Sun, Qiuge Zhang, Weitang Yuan, Xiaoli Li, Chen Chen, Yaxin Guo, Bo Shao, Qin Dang, Quanbo Zhou, Qisan Wang, Guixian Wang, Jinbo Liu, Quancheng Kan
ONCOLOGY. 2020 May 23 .
effect： 2.278
- STAT1-induced upregulation of lncRNA LINC01123 predicts poor prognosis and promotes the progression of endometrial cancer through miR-516b/KIF4A
Yuguang Yang, Jin Wu, Hongfeng Zhou, Wenming Liu, Jincai Wang, Qingyuan Zhang
Cell Cycle. 2020 May 13 ; 12
effect： 3.259
- Decreased expression and hypomethylation of HDAC9 lead to poor prognosis and inhibit immune cell infiltration in clear cell renal cell carcinoma
Yang Fu, Chiyuan Piao, Zhe Zhang, Yuyan Zhu, Shanshan Sun, Jianbin Bi, Chuize Kong, Min Ju
Urologic Oncology: Seminars and Original Investigations. 2020 May 08 .
effect： 2.863
- Towards a psychobiotic therapy for depression: Bifidobacterium breve CCFM1025 reverses chronic stress-induced depressive symptoms and gut microbial abnormalities in mice
Peijun Tian, Kenneth J.O'Riordan, Yuan-kun Lee, Gang Wang, Jianxin Zhao, Hao Zhang, John F.Cryan, Wei Chen
Neurobiology of Stress. 2020 May 01 .
- 依维莫司对乳腺癌拉帕替尼耐药逆转作用及其分子机制研究
徐婷
重庆医科大学. 2020 May 01 .
- NLRP3炎症小体/Caspase-1/Galectin-3信号通路参与糖尿病兔心房重构的上游机制研究
吴小寒
天津医科大学. 2020 May 01 .
- 雷公藤红素增强白血病多药耐药K562/ADR细胞对阿霉素敏感性的作用机制
刘婷
南华大学. 2020 May 01 .
- miR-21通过NF-κB信号通路影响血管紧张素Ⅱ诱导的肾小球系膜细胞炎症因子表达
彭君; 彭家清; 秦鹏; 罗先荣; 张敏
免疫学杂志. 2020 May 01 .
- SiRNA HO-1在无机砷抑制树突状细胞功能中的可能影响
张晨晨
中国医科大学. 2020 May 01 .
- MAPK通路在MC-LR诱导小鼠卵巢颗粒细胞凋亡中的作用
袁乐
郑州大学. 2020 May 01 .
- 巨噬细胞极化在实验性矽肺中的作用与机制
赵有亮
郑州大学. 2020 May 01 .
- 紫花牡荆素对MHCC97-H源性肝癌干样细胞性质和miR-139-5p表达的影响
周玲利
湖南师范大学. 2020 May 01 ; 1
- 幽门螺杆菌诱导的胃癌细胞源性外泌体中差异表达miRNA的筛选及初步鉴定
张洁雅
南华大学. 2020 May 01 ; 1
- 体外受精-胚胎移植对子代肝脏糖脂代谢的作用及机制研究
朱嵩岳
苏州大学. 2020 May 01 ; 2
- 氧化三甲胺与血管紧张素Ⅱ1型受体在动脉粥样硬化中的相互作用
李天翔
内蒙古医科大学. 2020 May 01 .
- 矽肺发病中外泌体miR-107对肺成纤维细胞转分化的作用及其机制
王迪
郑州大学. 2020 May 01 .
- Isodeoxyelephantopin, a sesquiterpene lactone from Elephantopus scaber Linn., inhibits pro-inflammatory mediators’ production through both NF-κB and AP-1 pathways in LPS-activated macrophages
Yixin Han, Ximeng Li, Xiaoyu Zhang, Yuan Gao, Ruijuan Qi, Runlan Cai, Yun Qi
International Immunopharmacology. 2020 Apr 18 .
effect： 3.361
- Silica particles disorganize the polarization of pulmonary macrophages in mice
Youliang Zhao, Changfu Hao, Lei Bao, Di Wang, Yiping Li, Yaqian Qu, Mingcui Ding, Ahui Zhao, WuYao
ECOTOX ENVIRON SAFE. 2020 Apr 15 .
effect： 4.527
- Terphenyllin Suppresses Orthotopic Pancreatic Tumor Growth and Prevents Metastasis in Mice
Jia Zhang, Weiyi Wang, Yuan Zhou, Jing Yang, Jingli Xu, Zhiyuan Xu, Beihua Xu, Li Yan, Xiang-Dong Cheng, Minghua Li, Jiang-Jiang Qin
Front Pharmacol. 2020 Apr 08 .
effect： 3.845
- Effect of CD44 on differentiation of human amniotic mesenchymal stem cells into chondrocytes via Smad and ERK signaling pathways
Yan Xu， Yi‑Qing Wang， Ai‑Tong Wang， Chang‑Yin Yu， Yi Luo， Ru‑Ming Liu， Yu‑Jie Zhao， Jian‑Hui Xiao
Mol Med Rep. 2020 Mar 30 .
effect： 1.851
- Cannabidiol alleviates hemorrhagic shock‐induced neural apoptosis in rats by inducing autophagy through activation of the PI3K/AKT pathway
Bo Lin,Youguang Gao, Zhiwang Li,Zhiming Zhang,Xianzhong Lin,Jinpeng Gao
Fundam Clin Pharmacol. 2020 Mar 25 .
- Mechanism of HMGB1–RAGE in Kawasaki disease with coronary artery injury
Biying Qian, Hua Huang, Mingye Cheng, Tingting Qin, Tao Chen, Jianmei Zhao
EUR J MED RES. 2020 Mar 17 ; 1
effect： 1.736
- 应用dsRNA干扰技术对旋毛虫Kazal型丝氨酸蛋白酶抑制剂基因功能的初步研究
于鹏成;刘畅;吴丽佳;伊娜娜;孙益春
中国兽医科学. 2020 Mar 16 .
- Interleukin-38 is elevated in inflammatory bowel diseases and suppresses intestinal inflammation
Cheng Xie, Wei Yan, Runze Quan, Chaoyue Chen, Lei Tua, Xiaohua Hou, Yu Fu
Cytokine. 2020 Mar 01 .
effect： 3.078
- 无机砷对J774A.1巨噬细胞自噬-溶酶体途径及其上游调控因子TFEB的影响
柳旭萍
中国医科大学. 2020 Mar 01 .
- 基于线粒体途径探讨白术内酯Ⅰ诱导U266细胞凋亡的机制
麦梓欣
广州中医药大学. 2020 Mar 01 .
- HMGB1/ERS信号通路在利福平诱导的小鼠肝损伤模型中的作用及其可能机制的研究
鲁桓兵
安徽医科大学. 2020 Mar 01 ; 2
- m6A去甲基酶FTO对GABAAR的调控在Mn致雌性大鼠青春期启动提前中的作用与机制
杨欣欣
中国医科大学. 2020 Mar 01 .
- CD44-RhoA-YAP信号通路调控纤维母细胞活化及其在实验性矽肺中的作用机制研究
李思怿
中国医科大学. 2020 Mar 01 .
- 砷和胆红素对神经元细胞内MAPK、PI3K、Nrf2信号通路的影响
盛紫依
中国医科大学. 2020 Feb 01 .
- 雄黄对大鼠原代肝细胞MAPK/Nrf2/HO-1信号通路的影响及人工牛黄的保护作用
马秀政
中国医科大学. 2020 Feb 01 .
- 雌激素通过GPER/PKA信号途径调节Min6细胞线粒体自噬的分子机制研究
李思怡
中国医科大学. 2020 Feb 01 .
- 长链非编码RNA SNHG14可能通过促进胃癌细胞增殖和转移影响胃癌的进展
渠辉恒; 王宁; 陈义钢; 陈烨; 夏加增
南京医科大学学报(自然科学版). 2020 Jan 15 .
- Modulating cancer stemness provides luminal a breast cancer cells with HER2 positive-like features
Yi Mei, Dongyan Cai, Xiaofeng Dai
Journal of Cancer. 2020 Jan 01 ; 5
- Cytoglobin overexpression facilitates proliferation and migration of vascular smooth muscle cells
Li Lei, Xie Yilin, Li Shen, Tan Juanjuan, Qin Yingchun, Yan Zhiqiang
ARCH BIOL SCI. 2020 Jan 01 .
effect： 0.554
- 双硫仑对口腔鳞癌细胞上皮-间充质转化的影响及机制探讨
王学梅, 蒋勇
上海口腔医学. 2020 Jan 01 ; 2
- Expression and localization of the MMP inhibitor RECK in a rat model of COPD: its involvement in the development of COPD
Z.-X. LI, X. WANG, X.-G. GUO, H.-Z. XIONG, T.-P. LI
EUR REV MED PHARMACO. 2020 Jan 01 .
effect： 3.024
- Protective properties of heme oxygenase-1 expressed in umbilical cord mesenchymal stem cells help restore the ovarian function of premature ovarian failure mice through activating the JNK/Bcl-2 signal pathwayregulated autophagy and upregulating the circulating of CD8+ CD28− T cells
Na Yin , Chenting Wu , Jianping Qiu , Yueming Zhang, Le Bo, Ying Xu, Mengdie Shi, Songyue Zhu, Guangzhao Yang, Caiping Mao
Stem Cell Research & Therapy. 2020 Jan 01 .
effect： 5.116
- TSH调节颗粒细胞分泌功能的机制研究
顾益惠
苏州大学. 2019/05/01 00:00:00 undefined undefined .
- TIMP1基因对肺炎链球菌诱导的肺泡上皮细胞HEPApiC凋亡的影响及机制研究
常大芸;刘学工;李宁华;王晓丽;戴蕾莲
临床肺科杂志. 2019 Dec 26 .
- LncRNA MIR4435‐2HG‐mediated upregulation of TGF‐β1 promotes migration and proliferation of nonsmall cell lung cancer cells
Mei Yang, Xiaohua He, Xiaoxian Huang, Jiyang Wang, Yuxin He, Li Wei
Environmental Toxicology. 2019 Dec 25 ; 5
effect： 2.649
- CDK4/6 Inhibitor Palbociclib Amplifies the Radiosensitivity to Nasopharyngeal Carcinoma Cells via Mediating Apoptosis and Suppressing DNA Damage Repair
Xianhe Xie, Weili Zheng, Ting Chen, Wanzun Lin, Ziyuan Liao, Junjin Liu, Yin Ding
Onco Targets Ther. 2019 Dec 16 .
- High hnRNP AB expression is associated with poor prognosis in patients with colorectal cancer
Jun‑Min Zhou, Hang Jiang, Tao Yuan, Guang‑Xun Zhou, Xiang‑Bing Li, Kun‑Ming Wen
Oncol Lett. 2019 Dec 01 ; 6
effect： 1.871
- Structure-based virtual screening and biological evaluation of novel non-bisphosphonate farnesyl pyrophosphate synthase inhibitors
Qingzhu Liu,Yinxing Miao,Xiaodan Wang,Gaochao Lv,Ying Peng,Ke Li,Ming Li,Ling Qiu,Jianguo Lin
EUR J MED CHEM. 2019 Nov 22 .
effect： 4.833
- 1,4-Dithiothreitol treatment ameliorates hematopoietic and intestinal injury in irradiated mice: Potential application of a treatment for acute radiation syndrome
Kui Li,Junling Zhang,Jian Cao,Xuejiao Li,Hongqi Tian
Int Immunopharmacol. 2019 Nov 01 .
effect： 3.361
- Genipin attenuates mitochondrial-dependent apoptosis, endoplasmic reticulum stress, and inflammation via the PI3K/AKT pathway in acute lung injury
Luo X,Lin B,Gao Y,Lei X,Wang X,Li Y,Li T
Int Immunopharmacol. 2019 Aug 26 .
effect： 3.361
- Detection of Aflatoxin adducts as potential markers and the role of curcumin in alleviating AFB1-induced liver damage in chickens
Sihong Li, Ishfaq Muhammad, Hongxiao Yu, Xiaoqi Sun, Xiuying Zhang
Ecotoxicology and Environmental Safety. 2019 Jul 30 .
effect： 3.13
- Upregulation of microRNA‑520a‑3p inhibits the proliferation, migration and invasion via spindle and kinetochore associated 2 in gastric cancer
Hui Su,Feng Ren,Haitao Jiang,Yunjie Chen,Xiaoxiang Fan
Oncology Letters. 2019 Jul 25 .
effect： 1.871
- 七氟烷后处理对大鼠心肌缺血再灌注损伤的保护作用及与NCX1的相关性研究
陈晓芳; 赵晓亮; 王涛; 徐志新
临床和实验医学杂志. 2019 Jul 10 .
- Genipin protects rats against lipopolysaccharide-induced acute lung injury by reinforcing autophagy
Zhijie Zhang, Xue Wang, Chengzhou Ma, Zhiwang Li, Huayong Chen, Zhiming Zhang, Tao Li
International Immunopharmacology. 2019 Jul 01 .
effect： 3.943
- ERK5易位在尼古丁促进高糖高脂诱导的H9c2细胞凋亡敏感性及纤维化机制研究
刘雯霞
山西医科大学. 2019 Jun 30 .
- 小分子激酶抑制剂的敏感性筛选及WH-4-023抗肝癌机制研究
马培元
山西医科大学. 2019 Jun 20 .
- 氯化两面针碱通过靶向miR-31治疗结肠炎的机制
吴亚俐
山西医科大学. 2019 Jun 12 .
- 二烯丙基三硫诱导甲状腺乳头状癌细胞凋亡及其分子机制的研究
潘洁
江南大学. 2019 Jun 01 .
- 旋毛虫ES抗原致小鼠DCs吲哚胺2，3-双加氧酶表达的影响
翟鹏
东北农业大学. 2019 Jun 01 .
- 姜黄素对氯胺酮致神经细胞损伤的保护作用及机制研究
陈宇
东北农业大学. 2019 Jun 01 .
- GM1经PI3K/AKT/GSK3β信号通路对幼龄大鼠氯胺酮麻醉的神经保护作用
刘文瀚
东北农业大学. 2019 Jun 01 .
- 载骨碎补总黄酮磷酸钙骨水泥对骨缺损模型大鼠诱导膜中成骨细胞分化的影响及其机制研究
董航;黄嘉华;麦喆钘;陈柏行;黄培镇
中国药房. 2019 May 29 ; 10
- miR-144靶向PIK3CD基因影响结直肠癌细胞增殖和细胞因子表达的作用机制
陈红跃; 杨萌萌; 张小路; 段铮
中国免疫学杂志. 2019 May 27 .
- 黄芪注射液介导Wnt/β-Catenin信号通路调控表皮干细胞增殖分化促进糖尿病溃疡愈合的机制研究
仇莲胤
上海中医药大学. 2019 May 20 ; 3
- T-2 toxin impairs male fertility by disrupting hypothalamic-pituitary-testis axis and
declining testicular function in mice
Xu Yang,Xuliang Zhang,Qiucheng Yao,Miao Song,Yanfei Han,Bing Shao,Yanfei Li
Chemosphere. 2019 May 04 .
effect： 4.427
- Predictable chronic mild stress promotes recovery from LPS-induced depression
Ruili Dang, Yan-yan Guo, Kun Zhang, Pei Jiang, Ming-gao Zhao
Molecular Brain . 2019 May 03 .
effect： 4.58
- Subchronic exposure to fluoride and arsenite induces oxidative stress and activates the Nrf2 signaling pathway in the kidneys of rat offspring
Xiao-lin Tian,Jing Feng,Ni-sha Dong,Yi Lv,Cai-ling Wei,Ben Li,Yan-qin Ma,Jia-xin Xie,Yu-lan Qiu,Guo-hua Song,Xue-feng Ren,Xiao-yan Yan
Science of The Total Environment. 2019 May 01 .
effect： 4.61
- 核不均一核糖核蛋白AB在结直肠癌中的表达及意义
周隽敏
遵义医科大学. 2019 May 01 .
- HMGB1/RAGE轴介导内质网应激PERK/eIF2α/ATF4信号通路在急性呼吸窘迫综合征中的作用机制研究
何飞
南京大学. 2019 May 01 .
- 红景天苷抗血小板活性及抗血栓作用的研究
林晓坚
贵州医科大学. 2019 May 01 .
- 转录因子KLF5在低氧条件下对人肺癌A549细胞糖代谢的影响及其机制
李响
南华大学. 2019 May 01 ; 1
- 人卵巢组织来源环状RNA的鉴定及其在卵巢衰老中的调控作用
蔡鸿财
华中科技大学. 2019 May 01 ; 4
- 长链非编码RNA PVT1通过调控miR-26b促进血管新生的机制研究
郑积富
南昌大学. 2019 May 01 .
- 小续命汤在急性脑缺血再灌注大鼠体内的物质基础研究及对肠道菌群结构特征的影响
罗晓雅
北京协和医学院. 2019 May 01 .
- Hsa_circ_0005075 predicts a poor prognosis
and acts as an oncogene in colorectal cancer
via activating Wnt/β-catenin pathway
Jin YD,Ren YR,Gao YX,Zhang L,Ding Z
Eur Rev Med Pharmacol Sci. 2019 Apr 01 ; 8
- HSP70在TGF-β诱导A549细胞EMT进程中的作用
任亚南
郑州大学. 2019 Apr 01 .
- Jaspine B衍生物ZE-2抑制胃癌细胞增殖作用机制的研究
班倩红
郑州大学. 2019 Apr 01 ; 7
- 杨芽黄素在LPS刺激的巨噬细胞中发挥抗炎作用的机制研究
侯睿
北京协和医学院. 2019 Apr 01 .
- 姜黄素抑制单核细胞浸润并减少单核细胞来源GRN分泌抗肝纤维化的机制研究
赵祥安
南京中医药大学. 2019 Mar 20 ; 8
- miR-134通过调控MMP1和MMP3表达抑制骨肉瘤侵袭和转移的作用及其相关机制研究
陈成龙
山西医科大学. 2019 Mar 17 .
- Niclosamide及其衍生物DK-520对RANKL诱导的破骨细胞早期融合及分化的影响
焦玉睿
山西医科大学. 2019 Mar 15 .
- 血清炎症因子与不伴有继发性干燥综合征的系统性红斑狼疮患者的干眼发生的相关性研究
王安
安徽医科大学. 2019 Mar 01 .
- Graves病患者血清外泌体通过Toll样受体介导免疫和炎症反应
黄明诗
中国医科大学. 2019 Mar 01 .
- 金黄色葡萄球菌杀白细胞素S组分通过C5aR抑制肝癌细胞增殖与侵袭作用的研究
于文伟
安徽医科大学. 2019 Mar 01 .
- 洋葱槲皮素抗炎活性及对NF-κB和Akt信号通路的影响
倪湾
锦州医科大学. 2019 Mar 01 ; 1
- 无机砷对树突状细胞抗原递呈功能的影响及p62依赖性Nrf2活化的可能调控作用
郭媛媛
中国医科大学. 2019 Mar 01 ; 2
- 无机砷影响树突状细胞自噬-溶酶体途径和转录因子EB的可能作用
赵璐
中国医科大学. 2019 Mar 01 .
- SP1-induced upregulation of long noncoding RNA LINC00313 contributes to papillary thyroid cancer progression via the miR-422a
DG Yan,N Liu,M Chao,Y.-Y. TU,W.-S. LIU1
Eur Rev Med Pharmacol Sci. 2019 Feb 01 ; 3
- 棕榈酸通过ROS/JNK途径调节MIN6细胞自噬的分子机制及作用研究
张媚
中国医科大学. 2019 Feb 01 ; 2
- Downregulation of G2/mitotic-specific cyclinB1 triggers autophagy via AMPK-ULK1-dependent signal pathway in nasopharyngeal carcinoma cells
Xianhe Xie,Wanzun Lin,Weili Zheng,Ting Chen,Haitao Yang,Lijun Sun,Fei Huang,Zili Wang,Heng Lin,Long Chen,Jun Liu,Liyan Yang
Cell Death Dis. 2019 Jan 30 ; 2
- 儿茶素对脂多糖诱导的BV-2 细胞炎性反应的作用
王青,贾哲琳,宋丽娟,尉杰忠,杨智超,姜维佳,肖保国,马存根
Acta Pharmaceutica Sinica. 2018 Dec 31 ; 2
effect： 6.014
- 1,25-Dihydroxy Vitamin D3 Attenuates the Oxidative Stress-Mediated Inflammation Induced by PM2.5via the p38/NF-κB/NLRP3 Pathway
Lili Xin, Bizhong Che, Bingzhong Zhai, Qiulin Luo, Chen Zhang, Jianshu Wang, Shengli Wang, Guoqiang Fan, Zhiyong Liu, Jialiang Feng & Zengli Zhang
Inflammation. 2018 Nov 14 .
effect： 2.618
- p38 MAPK信号通路在尼古丁诱导的血管内皮细胞自噬中的作用
王瑞玲; 刘雯霞; 刘彩红; 郭蕊; 王亚静
中国医学创新. 2018 Sep 15 .
- Clinical correlation of B7-H3 and B3GALT4 with the prognosis of colorectal cancer
Ting Zhang, Fang Wang, Jing-Yi Wu, Zhi-Chao Qiu, Yan Wang, Fen Liu, Xiao-Song Ge, Xiao-Wei Qi, Yong Mao, and Dong Hua
World J Gastroenterol. 2018 Aug 21 ; 31
- 葡萄籽原花青素单组分对PC12细胞的毒性研究
杨智超; 宋丽娟; 宋俊丽; 姜维佳; 王青
山西中医学院学报. 2018 Aug 14 .
- Effects of Fluoride on Autophagy in Mouse Sertoli Cells
Zhiyuan Feng,Chen Liang,Ram Kumar Manthari,Chong Wang,Jianhai Zhang
Biol Trace Elem Res. 2018 Jun 19 .
effect： 2.361
- AKBA诱导雪旺细胞ERK信号促进周围神经损伤修复的机制研究
张斌清
东北农业大学. 2018 Jun 01 .
- 硫化氢对棕榈酸诱导的HepG2细胞炎症信号通路的影响
秦玉
南华大学. 2018 May 01 .
- TGF-β1/Smad信号通路参与幽门螺杆菌Tipα诱导的胃癌细胞EMT形成
赵春莲
南华大学. 2018 May 01 .
- SPOP蛋白抑制肝癌细胞转移侵袭的分子机制探讨
纪丕友
福建医科大学. 2018 May 01 .
- Genistein与IGF1R抑制剂对前列腺癌放疗的协同增敏机制研究
唐启胜
中国人民解放军空军军医大学. 2018 May 01 .
- miR-497-3p靶向ATG7调控运动性心肌肥大的机制研究
张瑶
上海师范大学. 2018 May 01 ; 8
- PMPs对类风湿关节炎成纤维样滑膜细胞中RANKL/OPG系统的影响
王雯雯
扬州大学. 2018 Apr 13 .
- 通络醒脑泡腾片活性成分P-15通过自噬-溶酶体途径抗AD的机制研究
孟诗
成都中医药大学. 2018 Apr 01 .
- 葡萄籽原花青素口服治疗EAE的抗炎作用初探
贾哲琳
山西医科大学. 2018 Mar 24 .
- TAB1介导糖酵解在高糖诱导的骨髓来源巨噬细胞极化中的作用与机制
段分分
安徽医科大学. 2018 Mar 01 .
- 4-1BB信号通路调控巨噬细胞分泌细胞因子及其对矽肺纤维化影响的实验研究
路一平
中国医科大学. 2018 Mar 01 ; 12
- PCBP1-AS1通过TRAF5介导的NF-κB信号通路调控外阴鳞癌细胞生物学行为的机制研究
王洪雨
中国医科大学. 2018 Mar 01 .
- 三七总皂苷对氧诱导新生小鼠视网膜病变新生血管的作用
田丽敏
湖北民族学院. 2017 Jun 30 .
- 白杨素对氧化应激诱导的血管内皮损伤的保护作用
张夏丽
山西医科大学. 2017 Jun 19 .
- 两种新型有机污染物的环境生物分析方法研究
梁亚如
江苏大学. 2017 Jun 02 ; 1
- MAPK信号通路在高糖高脂诱导的心肌细胞肥大中的差异调节作用
闫佳敏,瑞玲,马琴,崔桂丽,王亚静
中国医学创新. 2017 May 26 ; 10
- PMPs通过CXCR2介导的信号通路促进RA-FLS的迁移、侵袭
柳桂萍
扬州大学. 2017 Apr 05 ; 1
- Calpain-2在运动改善肝脏内质网应激中的作用及相关机制研究
张亨
上海师范大学. 2017 Mar 01 ; 1
- Dexmedetomidine attenuates lipopolysaccharide-induced acute lung injury by inhibiting oxidative stress, mitochondrial dysfunction and apoptosis in rats
Chunlai Fu,Xingui Dai,You Yang,Mengxiang Lin,Yeping Cai,Shaoxi Cai
Mol Med Rep. 2017 Jan 19 ; 1
effect： 1.92
- Neuroprotective effects of polydatin against mitochondrial-dependent apoptosis in the rat cerebral cortex following ischemia/reperfusion injury
YOUGUANG GAO,TING CHEN1,XIANGHUI LEI,YUNFENG LI,XINGUI DAI,YUANYUAN CAO,QIONGLEI DING,XIABAO LEI,TAO LI,XIANZHONG LIN
Mol Med Rep. 2016 Dec 09 ; 6
effect： 1.922
- Emulsified isoflurane alleviates rat islet beta cell RIN-m5F apoptosis induced by glucose via inhibiting endoplasmic reticulum stress
Wenyan Dong, Zhenkun Yang, Jingjing Zhao, Jie Sun, Min Yao, Shuoxiong Wu
Research Square.
- The p62/Keap1/Nrf2 axis in the control of C-2 induced human gastric cancer cell death switching between autophagy and apoptosis
ZhenYa Wang, Yong Guo, En Zhang, QianHong Ban, MengLin Wang, XinXin Wu, Lu Yu, Lu Liu, HaiYang Yu, Gi-You, ng Kim, YungHyun Choi, YiChao Xu, HongDe Xu, Cheng-Yun Jin
.
- Streptococcus thermophilus MN-ZLW-002 can inhibit pre-adipocyte differentiation through macrophage activation
Xiaohong Kang, Huijing Liang, Yating Luo, Zhouyong Li, Fang He, Xue Han, Lanwei Zhang
BIOL PHARM BULL.
effect： 1.863
- Dietary milk fat globule membrane regulates JNK and PI3K/Akt pathway and ameliorates type 2 diabetes in mice induced by a high-fat diet and streptozotocin
Q Yuan, B Zhan, M Du, R Chang, T Li, X Mao
Journal of Functional Foods.
effect： 4.451
- Yangonin modulates lipid homeostasis, ameliorates cholestasis and cellular senescence in alcoholic liver disease via activating nuclear receptor FXR
LinaKong,RenchaoDong,KaiHuang,XiaohuiWang,DalongWang,NanYue,Changyuan Wang,Pengyuan Sun,Jiang,ningGu,HaifengLuo,KexinLiu,JingjingWu,HuijunSun,QiangMeng
Phytomedicine.
effect： 5.340
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